Andrew's Blog

PURSUE ULTIMATE FACTS

2023-02-09
Lifter of My Head

Lifter of My Head
by Daniel Brunz

LORD, so many are rising up against me
Many are they who say of my soul
There is no help for me in God

When they throw stones at me
I need not fear nor flee

For You, O LORD, are a shield for me
My glory, and the lifter of my head
For You, O LORD, are a shield for me
My glory, and the lifter of my head

I cried to the LORD with my voice
And He heard me, He heard me, He heard me
And I cried to the LORD with my voice
And He heard me, He heard me, He answered me

And I lay down and slept
And I awoke for Your presence sustained me

So when ten thousand fight me
I need not fear nor flee

So when ten thousand fight me
I need not fear nor flee

So when ten thousand fight me
I need not fear nor flee

For You, O LORD, are a shield for me
My glory, and the lifter of my head
For You, O LORD, are a shield for me
My glory, and the lifter of my head

Arise, O LORD, and save me, O my God
For You have struck my enemies
You have broken their teeth
For salvation comes from You alone
Your blessing is upon Your people forever

永恒主啊，我的敌人何其多呀！
有许多人起来攻击我。

有许多人议论我说：
『他是不能由上帝得救助的。』
（细拉）

但是你呢、永恒主啊，
你是我四围的盾牌；
你是我的光荣，是让我抬起头来的。
我出声呼求永恒主，
他从他的圣山上应了我。
（细拉）

我躺下，我睡觉，我醒来，
都因永恒主在扶持着我。
虽有千万族民周围排列攻击我，
我也不怕。

永恒主啊，求你起来；
我的上帝啊，拯救我哦；
因为你击打了我众仇敌的腮骨，
你敲碎了恶人的牙齿。

拯救属于永恒主；
愿你的祝福在你人民身上。
（细拉）

(诗篇 3:1-8 吕振中)

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2023-02-07
プラネット

どうやって？こうやって。また、ほら、君と話そうか？
あれだって、これだって、今すぐ気付いてくれ
僕は君のプラネット、回り続けて
いつも君のそばで、黒点数えてたけれど
サヨナラなんてないよ……今日から軌道を外れんだ
最後まで見送ってよ、永遠に離れてくんだ


ラ…ララ…ララララララ…ラ…ララ…ラララララ…
ラ…ララ…ララララララ…ラ…ララ…ラララララ…


どうなって？こうなって。結局、独り佇んで
失って、勘づいて、今さら、戻れやしない
君のいない場所で、途方に暮れて
もう一度引力を、感じたかったんだけれど
神様なんていないよ、いつまで待っても巡回中
選ばれない悲しみを、何度でも噛みしめるんだ


君は僕の太陽、全てを燃やしたけれど
サヨナラなんてないよ、今日から軌道を外れんだ
最後まで見送ってよ、永遠に離れてくんだ


ラ…ララ…ララララララ…ラ…ララ…ラララララ…
ラ…ララ…ララララララ…ラ…ララ…ラララララ…


ラ…ララ…ララララララ…ラ…ララ…ラララララ…


ーープラネット - ラムジ

怎麼做？這麼做。嗯。現在還能和你說話吧？
那樣也好。這樣也好。真希望現在你能快點覺察到我。
我是一顆行星，不停地圍繞你轉動。
我本會一直在你的身邊，即使只是細數著你的黑子。
不說再見……今天我要開始偏離你的軌道。
目送我直到最後吧。因為我將要永遠與你分離。


啦…啦啦…啦啦啦啦啦啦…啦…啦啦…啦啦啦啦啦…
啦…啦啦…啦啦啦啦啦啦…啦…啦啦…啦啦啦啦啦…


變成怎樣？變成那樣。最終仍舊是我獨自一人佇立在這。
失去之後，才意識到。事到如今，再也回不去了。
在沒有你的場所，我完全不知所措。
你對我的引力，到現在都還想感受一下。
可是這世上並沒有什麼神明。無論期盼到何時都只能在自己的軌道中巡迴。
無法選擇的悲傷，究竟還要再嘗多少次？


你就是我的太陽。已將我的全部燃盡。
不說再見。從今天起就要偏離你的軌道。
目送我直到最後吧。因為我將要永遠與你分離。


啦…啦啦…啦啦啦啦啦啦…啦…啦啦…啦啦啦啦啦…
啦…啦啦…啦啦啦啦啦啦…啦…啦啦…啦啦啦啦啦…


啦…啦啦…啦啦啦啦啦啦…啦…啦啦…啦啦啦啦啦…


ーープラネット - ラムジ

How should I do it? Like this, maybe.
Hey, shall we talk again?
That, and this too—please notice me now.
I’m your planet, endlessly revolving,
Always by your side, counting the dark spots.


There’s no such thing as goodbye…
From today on, I’m leaving this orbit.
Watch me until the very end—
I’m drifting away forever.


La… la la… la lalalalala… la… la la… la lalalalala…
La… la la… la lalalalala… la… la la… la lalalalala…


What happened? It turned out this way.
In the end, I stand here alone.
Losing you, realizing it—
Now it’s already too late to go back.
In a place where you’re not, I’m at a loss,
I just wanted to feel that gravity once more.


There’s no such thing as God—
No matter how long I wait, He’s only on patrol.
The sorrow of not being chosen,
I chew on it again and again.


You are my sun, you burned everything away, but—
There’s no such thing as goodbye.
From today on, I’m leaving this orbit.
Watch me until the very end—
I’m drifting away forever.


La… la la… la lalalalala… la… la la… la lalalalala…
La… la la… la lalalalala… la… la la… la lalalalala…


La… la la… la lalalalala… la… la la… la lalalalala…

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2023-02-07
Kiss the Son

Kiss the Son
by Daniel Brunz

Why do the nations rage?
And why do the people plot in vain?
The kingdoms of earth align themselves against the LORD and His Messiah
Trying to defy His power and erase the Word that He’s set down
But He who sits in heaven just laughs
He just laughs

He’ll warn them in His wrath
And he will say…

I have placed my King in heaven before whom all knees shall bow
I have placed my King in heaven, King of Kings and Lord of Lords
I have placed my King in heaven, President of Presidents
I have placed my King in heaven

For God has said, “You are my son”
For God has said to Jesus, “You’re my son”
So ask of Me and I will give You all the nations of the world
Ask of Me and I will give You all the nations of the world
Ask of Me and I will give You all the nations of the world
Ask of Me and I will give You…

For the earth is the LORD’s and the fullness thereof
For the earth is the LORD’s and the fullness thereof
For the earth is the LORD’s and the fullness thereof
For the earth is the LORD’s

What rises up against the LORD will come back to earth where it belongs
For He will not share His glory with another, much less with foolish men
For the LORD is God, Jesus is King
And no new trend or political scheme will ever amount to more than dirt
Compared to the wisdom of His Word
For there’s nothing new under the sun
Men just rearrange what’s already been done
For God created the heart of man
And everything’s under His command
So to those who try to dethrone God: His Word will stand!

He will rule them with a rod of iron and shatter them like clay
He will rule them with a rod of iron and shatter them like clay
Just like it’s nothing
He’ll set them down
In their place

So be wise you kingdoms of the earth
So be wise you Hollywoods of earth
So be wise you rock stars of the earth
So be wise you politicians of earth

And worship the LORD in fear, and rejoice with trembling
And worship the LORD in fear, and rejoice with trembling

And kiss the Son, yeah, kiss the Son, kiss the Son, yeah, Kiss the Son
And kiss the Son, yeah, kiss the Son, kiss the Son, yeah, Kiss the Son
And kiss the Son, yeah, kiss the Son, kiss the Son, yeah, Kiss the Son
And kiss the Son, yeah, kiss the Son…

For the earth is the LORD’s and the fullness thereof
For the earth is the LORD’s and the fullness thereof
For the earth is the LORD’s and the fullness thereof
For the earth is the LORD’s

And worship the LORD in fear, and rejoice with trembling
And worship the LORD in fear, and rejoice with trembling

And kiss the Son, yeah, kiss the Son, kiss the Son, yeah, Kiss the Son
And kiss the Son, yeah, kiss the Son, kiss the Son, yeah, Kiss the Son
And kiss the Son, yeah, kiss the Son, kiss the Son, yeah, Kiss the Son
And kiss the Son, yeah, kiss the Son…

And He won’t be angry and You won’t perish in your way
For His wrath can come at once

Happy are those who trust in Him
Happy are those who trust in Him
Happy are those who trust in Him

The fear of the LORD is the beginning of wisdom

列国为什么彼此串通？
万族之民为什么谋算
不能成功的事呢？
地上君王列阵站着，
众人君一同阴谋，
要敌挡永恒主，敌挡他所膏立的，说：
『我们来挣开他们的捆绑，
来脱掉他们的绳索吧。』

那坐在天上的必冷笑；
永恒主必嗤笑他们。
那时他必气忿忿责备他们，
必发烈怒使他们惊惶；
传谕旨说：
『我，我已立我的君王
于锡安、我的圣山上。』
受膏者说：『我必传永恒主的谕旨；
永恒主曾对我说：「你是我的儿子，
我今日生了你。
你求我，我便将列国赐给你为产业，
将地极作为你的田产。
你必用铁杖打破他们；
你必摔碎他们、如窰匠的瓦器。」』

现在呢、君王啊，你们要机警些；
地上审判官哪，你们该听忠告。
要存畏惧心来事奉永恒主，
要战兢兢快乐，
要纯诚诚亲嘴拜服，
恐怕他发怒，你们就在路中灭亡；
因为他的怒气很快就要发作。

凡避难于他里面的都有福啊。

(诗篇 2:1-12 吕振中)

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2023-02-07
Everything He Does Shall Prosper

Everything He Does Shall Prosper
by Lance Edward

Blessed is the man who does not heed the counsel of this world
Blessed is the man who does not conform to worldly ways

For his delight is in the law of the LORD
And on His Word he meditates day and night

And he shall be like a tree by streams of water
That yields abundant fruit in every season
And his leaves shall never, never wither
And everything he does shall prosper
And everything he does shall prosper
And everything he does shall prosper

But the wicked are not so
For they are like the chaff the wind blows away
And the wicked shall not stand in the judgment
For the LORD knows the way of the righteous
But the evil ways of man shall pass away
Shall pass away
They’ll pass away
Forever

不依恶人的计谋而行，
不站在罪人的道路，
不坐在亵慢人的座位，
这人有福啊！
他所喜爱的、是永恒主的律法，
他昼夜所思想的、也是主的律法。

他好像一棵树、移植于流水沟旁，
按节候结果子，
其叶子总不凋残；
凡他所作的、尽都顺利。

恶人却不是这样：
恶人乃像糠粃、给风吹散而飘荡。
因此当审判时、恶人必站不住：
在义人会中、罪人必立不住脚。
因为永恒主知照义人的道路；
恶人的道路必灭没。

(诗篇 1:1-6 吕振中)

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2023-02-04
Add Tabs to My Blog

In [ ]:
cd hexo
In [ ]:
git clone https://github.com/next-theme/hexo-theme-next themes/next

Cloning into 'themes/next'...
remote: Enumerating objects: 6276, done.
remote: Counting objects: 100% (187/187), done.
remote: Compressing objects: 100% (114/114), done.
remote: Total 6276 (delta 76), reused 156 (delta 68), pack-reused 6089
Receiving objects: 100% (6276/6276), 1.31 MiB | 949.00 KiB/s, done.
Resolving deltas: 100% (4051/4051), done.
In [ ]:
mkdir -p themes/freemind/scripts/tags
In [ ]:
cat << EOF > themes/freemind/scripts/tags/index.js
/* global hexo */

'use strict';

const postTabs = require('./tabs')(hexo);

hexo.extend.tag.register('tabs', postTabs, true);
hexo.extend.tag.register('subtabs', postTabs, true);
hexo.extend.tag.register('subsubtabs', postTabs, true);
EOF
In [ ]:
touch themes/freemind/scripts/tags/tabs.js
In [ ]:
cat themes/freemind/scripts/tags/tabs.js

/**
 * tabs.js | https://theme-next.js.org/docs/tag-plugins/tabs
 */

'use strict';

module.exports = ctx => function(args, content = '') {
  const tabBlock = /<!--\s*tab (.*?)\s*-->\n([\w\W\s\S]*?)<!--\s*endtab\s*-->/g;

  args = args.join(' ').split(',');
  const tabName = args[0];
  const tabActive = Number(args[1]) || 0;

  let tabId = 0;
  let tabNav = '';
  let tabContent = '';

  if (!tabName) ctx.log.warn('Tabs block must have unique name!');
  const matches = content.matchAll(tabBlock);

  for (const match of matches) {
    let [caption = '', icon = ''] = match[1].split('@');
    let postContent = match[2];

    postContent = ctx.render.renderSync({ text: postContent, engine: 'markdown' }).trim();

    const abbr = tabName + ' ' + ++tabId;
    const href = abbr.toLowerCase().split(' ').join('-');

    icon = icon.trim();
    if (icon.length > 0) {
      if (!icon.startsWith('fa')) icon = 'fa fa-' + icon;
      icon = `<i class="${icon}"></i>`;
    }

    caption = icon + caption.trim();

    const isActive = (tabActive > 0 && tabActive === tabId) || (tabActive === 0 && tabId === 1) ? ' active' : '';
    tabNav += `<li class="tab${isActive}"><a href="#${href}">${caption || abbr}</a></li>`;
    tabContent += `<div class="tab-pane${isActive}" id="${href}">${postContent}</div>`;
  }

  tabNav = `<ul class="nav-tabs">${tabNav}</ul>`;
  tabContent = `<div class="tab-content">${tabContent}</div>`;

  return `<div class="tabs" id="${tabName.toLowerCase().split(' ').join('-')}">${tabNav + tabContent}</div>`;
};

Here is English.

这里是中文。

ここは日本語テキストです。

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2022-10-18
Try Bacalhau

In [ ]:
curl -sL https://get.bacalhau.org/install.sh | bash

Your system is darwin_amd64
No BACALHAU detected. Installing fresh BACALHAU CLI...
Getting the latest BACALHAU CLI...
Installing v0.3.3 BACALHAU CLI...
Downloading https://github.com/filecoin-project/bacalhau/releases/download/v0.3.3/bacalhau_v0.3.3_darwin_amd64.tar.gz ...
Downloading sig file https://github.com/filecoin-project/bacalhau/releases/download/v0.3.3/bacalhau_v0.3.3_darwin_amd64.tar.gz.signature.sha256 ...
Verified OK
Extracting tarball ...
NOT verifying Bin
bacalhau installed into /usr/local/bin successfully.
Client Version: v0.3.3
Server Version: v0.3.3
In [ ]:
bacalhau version

Client Version: v0.3.3
Server Version: v0.3.3

Compile Bacalhau CLI into WebAssembly Binaries

In [ ]:
import os
from EdgeGPT import Chatbot as Bing, ConversationStyle

bing = Bing(cookiePath = os.path.expanduser('~/.config/EdgeGPT/cookies.json'))
In [ ]:
res = (await bing.ask(
    prompt = '''
Simulate the process of compiling Bacalhau CLI into WebAssembly Binaries. And summarize your actions and results.
''',
    conversation_style = ConversationStyle.balanced,
))['item']['messages'][1]

print(res['text'])
print('\n---\n')
print(res['adaptiveCards'][0]['body'][0]['text'])

Compiling Bacalhau CLI into WebAssembly binaries is a multi-step process. Here are the steps:

1. Install Rust and wasm-pack. You can install Rust from [here](https://www.rust-lang.org/tools/install) and wasm-pack from [here](https://rustwasm.github.io/wasm-pack/installer/).

2. Clone the Bacalhau CLI repository from [here](https://github.com/bacalhau-crypto/bacalhau-cli).

3. Navigate to the cloned repository and run the following command to build the WebAssembly binaries:

   ```
   wasm-pack build --target web
   ```

   This command will compile the Rust code into WebAssembly binaries and create a JavaScript wrapper for the WebAssembly module.

4. The compiled WebAssembly binaries will be located in the `pkg` directory.

5. To use the compiled WebAssembly binaries in a web application, you can import the JavaScript wrapper and use the exported functions.

I hope this helps! Let me know if you have any other questions.

---

Compiling Bacalhau CLI into WebAssembly binaries is a multi-step process. Here are the steps:

1. Install Rust and wasm-pack. You can install Rust from [here](https://www.rust-lang.org/tools/install) and wasm-pack from [here](https://rustwasm.github.io/wasm-pack/installer/).

2. Clone the Bacalhau CLI repository from [here](https://github.com/bacalhau-crypto/bacalhau-cli).

3. Navigate to the cloned repository and run the following command to build the WebAssembly binaries:

   ```
   wasm-pack build --target web
   ```

   This command will compile the Rust code into WebAssembly binaries and create a JavaScript wrapper for the WebAssembly module.

4. The compiled WebAssembly binaries will be located in the `pkg` directory.

5. To use the compiled WebAssembly binaries in a web application, you can import the JavaScript wrapper and use the exported functions.

I hope this helps! Let me know if you have any other questions.
In [ ]:
res = (await bing.ask(
    prompt = '''
Teach me how to compile Bacalhau CLI into WebAssembly Binaries. And summarize your actions and results.
''',
    conversation_style = ConversationStyle.balanced,
))['item']['messages'][1]

print(res['text'])
print('\n---\n')
print(res['adaptiveCards'][0]['body'][0]['text'])

Sure, I can help you with that. Here are the steps to compile Bacalhau CLI into WebAssembly binaries:

1. Install Rust and wasm-pack. You can install Rust from [here](https://www.rust-lang.org/tools/install) and wasm-pack from [here](https://rustwasm.github.io/wasm-pack/installer/).

2. Clone the Bacalhau CLI repository from [here](https://github.com/bacalhau-crypto/bacalhau-cli).

3. Navigate to the cloned repository and run the following command to build the WebAssembly binaries:

   ```
   wasm-pack build --target web
   ```

   This command will compile the Rust code into WebAssembly binaries and create a JavaScript wrapper for the WebAssembly module.

4. The compiled WebAssembly binaries will be located in the `pkg` directory.

5. To use the compiled WebAssembly binaries in a web application, you can import the JavaScript wrapper and use the exported functions.

I hope this helps! Let me know if you have any other questions.

---

Sure, I can help you with that. Here are the steps to compile Bacalhau CLI into WebAssembly binaries:

1. Install Rust and wasm-pack. You can install Rust from [here](https://www.rust-lang.org/tools/install) and wasm-pack from [here](https://rustwasm.github.io/wasm-pack/installer/).

2. Clone the Bacalhau CLI repository from [here](https://github.com/bacalhau-crypto/bacalhau-cli).

3. Navigate to the cloned repository and run the following command to build the WebAssembly binaries:

   ```
   wasm-pack build --target web
   ```

   This command will compile the Rust code into WebAssembly binaries and create a JavaScript wrapper for the WebAssembly module.

4. The compiled WebAssembly binaries will be located in the `pkg` directory.

5. To use the compiled WebAssembly binaries in a web application, you can import the JavaScript wrapper and use the exported functions.

I hope this helps! Let me know if you have any other questions.
In [ ]:
res = (await bing.ask(
    prompt = '''
介绍 Bacalhau CLI。如何将 Bacalhau CLI 编译成 WebAssembly 二进制文件？总结你的步骤和结果。
''',
    conversation_style = ConversationStyle.balanced,
))['item']['messages'][1]

print(res['text'])
print('\n---\n')
print(res['adaptiveCards'][0]['body'][0]['text'])

Bacalhau CLI 是一个用于在 Bacalhau 平台上运行任务的命令行工具。根据 Bacalhau 的文档，你需要将你的程序编译成 WASI-compliant WebAssembly。你可以查看你的编译器的说明来了解如何执行此操作。例如，Rust 用户可以指定 wasm32-wasi 目标来 rustup 和 cargo 来编译为 WASI WebAssembly [^2^]。

你可以参考这篇文章 [^9^] 和这篇文章 [^10^] 来了解如何将 C++ 项目编译成 WebAssembly。这篇文章 [^11^] 可以让你更好地了解 WebAssembly。

---

[1]: https://developer.mozilla.org/zh-CN/docs/WebAssembly/C_to_wasm "编译 C/C++ 为 WebAssembly - WebAssembly | MDN"
[2]: https://docs.bacalhau.org/getting-started/wasm-workload-onboarding/ "Onboarding Your WebAssembly Workloads | Bacalhau Docs"
[3]: https://github.com/bacalhau-project/bacalhau "GitHub - bacalhau-project/bacalhau: Compute over Data framework for ..."
[4]: https://zhuanlan.zhihu.com/p/258560278 "记一次完整 C++ 项目编译成 WebAssembly 的实践 - 知乎"
[5]: https://developer.mozilla.org/zh-CN/docs/WebAssembly/C_to_wasm "编译 C/C++ 为 WebAssembly - WebAssembly | MDN"
[6]: https://docs.bacalhau.org/getting-started/wasm-workload-onboarding/ "Onboarding Your WebAssembly Workloads | Bacalhau Docs"
[7]: https://github.com/bacalhau-project/bacalhau "GitHub - bacalhau-project/bacalhau: Compute over Data framework for ..."
[8]: https://juejin.cn/post/7013286944553566215 "快 11K Star 的 WebAssembly，你应该这样学 - 掘金"
[9]: https://juejin.cn/post/7013286944553566215 "快 11K Star 的 WebAssembly，你应该这样学 - 掘金"
[10]: https://juejin.cn/post/6914148755738460168 "c++项目转成wasm全过程 - 掘金"
[11]: https://www.jianshu.com/p/bff8aa23fe4d "几张图让你看懂WebAssembly - 简书"

Bacalhau CLI 是一个用于在 Bacalhau 平台上运行任务的命令行工具。根据 Bacalhau 的文档，你需要将你的程序编译成 WASI-compliant WebAssembly。你可以查看你的编译器的说明来了解如何执行此操作。例如，Rust 用户可以指定 wasm32-wasi 目标来 rustup 和 cargo 来编译为 WASI WebAssembly [^1^][2]。

你可以参考这篇文章 [^2^][9] 和这篇文章 [^3^][10] 来了解如何将 C++ 项目编译成 WebAssembly。这篇文章 [^4^][11] 可以让你更好地了解 WebAssembly。
Read More

2022-10-02
Research History of Synaptotagmin-7

Synaptotagmins, such as SYT7, are calcium-dependent phospholipid-binding proteins known for their role in synaptic exocytosis and neurotransmitter release. Significant expression has also been observed in the prostate and other tissues.
—— Wikipedia - Synaptotagmin-7

Two different monoclonal antibodies¹, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton² protein, which is exposed on the outer surface of brain synaptic vesicles.
Immunocytochemical experiments³ at the electron microscope level demonstrate that these antibodies⁴ bind the vesicles in many different types of nerve terminals.
The antibodies have been used successfully to purify synaptic vesicles from crude brain homogenates by immunoprecipitation⁵ onto the surface of polyacrylamide beads⁶.
The profiles of the structures precipitated by these beads are almost exclusively vesicular, confirming the vesicle-specificity of the antibodies. In SDS gels⁷, the antibodies bind a single protein of 65,000 daltons.
The two antibodies are not identical, but compete for binding sites on this protein.

Immune competition experiments also demonstrate that the antigenic components⁸ on the 65,000-dalton protein are widely distributed in neuronal and neural secretory tissues. Detectable antigen⁸ is not found in uninnervated tissue - blood cells and extrajunctional muscle.
Low levels are found in nonneural secretory tissues; it is not certain whether this reflects the presence of low amounts of the antigen on all the exocytotic vesicles in these tissues or whether the antigen is found only in neuronal fibers within these tissues.
The molecular weight and at least two antigenic determinants of the 65,000-dalton protein are highly conserved throughout vertebrate phylogeny⁹.
The two antibodies recognize a 65,000-dalton protein present in shark, amphibia, birds, and mammals.
The highly conserved nature of the determinants on this protein and their specific localization on secretory vesicles of many different types suggest that this protein may be essential for the normal function of neuronal secretory vesicles.

—— Matthew, W D, L Tsavaler, and L F Reichardt. “Identification of a Synaptic Vesicle-Specific Membrane Protein with a Wide Distribution in Neuronal and Neurosecretory Tissue.” Journal of Cell Biology 91, no. 1 (October 1, 1981): 257–69. https://doi.org/10.1083/jcb.91.1.257.

¹ monoclonal antibodies =>

A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell line made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.

—— Wikipedia - Monoclonal antibody

⁴ antibodies

² dalton =>

The dalton or unified atomic mass unit (symbols: Da or u) is a unit of mass widely used in physics and chemistry. It is defined as 1/12 of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at rest.

—— Wikipedia - Dalton (unit)

³ Immunocytochemical experiments =>

Immunocytochemistry (ICC) is a common laboratory technique that is used to anatomically visualize the localization of a specific protein or antigen in cells by use of a specific primary antibody that binds to it. The primary antibody allows visualization of the protein under a fluorescence microscope when it is bound by a secondary antibody that has a conjugated fluorophore. ICC allows researchers to evaluate whether or not cells in a particular sample express the antigen in question. In cases where an immunopositive signal is found, ICC also allows researchers to determine which sub-cellular compartments are expressing the antigen.

—— Wikipedia - Immunocytochemistry

⁴ antibodies =>

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses.

—— Wikipedia - Antibody

⁵ immunoprecipitation =>

Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein. This process can be used to isolate and concentrate a particular protein from a sample containing many thousands of different proteins. Immunoprecipitation requires that the antibody be coupled to a solid substrate at some point in the procedure.

—— Wikipedia - Immunoprecipitation

⁶ polyacrylamide beads =>

Polyacrylamide (abbreviated as PAM) is a polymer with the formula (-CH2CHCONH2-). It has a linear-chain structure. PAM is highly water-absorbent, forming a soft gel when hydrated.

—— Wikipedia - Polyacrylamide

⁷ SDS gels =>

SDS-PAGE (sodium dodecyl sulfate–polyacrylamide gel electrophoresis) is a discontinuous electrophoretic system developed by Ulrich K. Laemmli which is commonly used as a method to separate proteins with molecular masses between 5 and 250 kDa. The combined use of sodium dodecyl sulfate (SDS, also known as sodium lauryl sulfate) and polyacrylamide gel allows to eliminate the influence of structure and charge, and proteins are separated solely on the basis of differences in their molecular weight.

—— Wikipedia - SDS-PAGE

⁸ antigenic components =>

⁸ antigen =>

In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term antigen originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids.

—— Wikipedia - Antigen

⁹ vertebrate phylogeny =>

A phylogenetic tree (also phylogeny or evolutionary tree) is a branching diagram or a tree showing the evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical or genetic characteristics. All life on Earth is part of a single phylogenetic tree, indicating common ancestry.

—— Wikipedia - Phylogenetic tree

Read More

2022-09-23
In Search of Memory

In Search of Memory: The Emergence of a New Science of Mind.

  • Kandel, E. R. (2006). In Search of Memory: The Emergence of a New Science of Mind. New York: W. W. Norton & Company.

Synaptic strength is not fixed.

Consolidation
  • The first rigorous test of memory consolidation came in 1949, when the American psychologist C. P. Duncan applied electrical stimuli to the brain of animals during or immediately after training, resulting in convulsions that disrupted memory and caused retrograde amnesia. Producing seizures several hours after training had little or no effect on recall.
  • Almost twenty years later, Louis Flexner at the University of Pennsylvania made the remarkable discovery that drugs that inhibit the synthesis of proteins in the brain disrupt long-term memory if given during and shortly after learning, but they do not disrupt short-term memory. This finding suggested that long-term memory storage requires the synthesis of new proteins.
  • Together, the two sets of studies seemed to confirm the idea that memory storage takes place in at least two stages: a short-term memory lasting minutes is converted -- by a process of consolidation that requires the synthesis of new protein -- into stable, long-term memory lasting days, weeks, or even longer.
Same Storage Sites?
  • Carew, Castellucci, and I found that the same synaptic connections between sensory and motor neurons that are altered in short-term habituation and sensitization are also altered in long-term habituation and sensitization. Moreover, in both cases, the synaptic changes parallel the changes in behavior we observed: in long-term habituation, the synapse is depressed for a period of weeks, whereas in long-term sensitization, it is enhanced for weeks. This suggested that, in the simplest cases, the same site can store both short- and long-term memory and that it can do so for different forms of learning.
Mechanism?
  • Bailey and his colleague, Mary Chen, and Carew and I found that long-term memory is not simply an extension of short-term memory: not only do the changes in synaptic strength last longer but, more amazingly, the actual number of synapses in the circuit changes. Specifically, in long-term habituation the number of presynaptic connections among sensory neurons and motor neurons decreases, whereas in long-term sensitization sensory neurons grow new connections that persist as long as the memory is retained. There is in each case a parallel set of changes in the motor cell.
  • Functional Changes vs. Anatomical Changes
Molecules and Short-Term Memory
  • Release more or less transmitter?
  • Increase/decrease number of receptors?
  • Increase/decrease sensitivity of receptors?

We found that the change is quite one-sided: during short-term habituation lasting minutes, the sensory neuron releases less neurotransmitter, and during short-term sensitization it releases more neurotransmitter.

How? Biochemical Signaling Pathways? By cyclic AMP?

Injected an inhibitor of PKA into a sensory neuron and found that it indeed blocked the ability of serotonin to enhance glutamate release.

In finding that cyclic AMP and protein kinase A are both necessary and sufficient for strengthening the connections between sensory and motor neurons, we were able to identify the first links in the chain of biochemical events leading to short-term memory storage.

Similarly in Mice Hippocampus

In both Aplysia and mice, the late phase of long-term potentiation is strongly affected by modulatory interneurons, which in mice are recruited to switch a short-term, homosynaptic into long-term, heterosynaptic change. In mice those neurons release dopamine, a neurotransmitter commonly recruited in the mammalian brain for attention and reinforcement. Like serotonin in Aplysia, dopamine prompts a receptor in the hippocampus to activate an enzyme that increases the amount of cyclic AMP. However, an important part of the increase in cyclic AMP in the mouse hippocampus occurs in the postsynaptic cell, whereas in Aplysia the increase occurs in the presynaptic sensory neuron. In each case, the cyclic AMP recruits protein kinase A and other protein kinases, which leads to the activation of CREB and the turning on of effector genes.

Memory Genes and Long-Term Memory

Gene Expression

We summarized our views in "The Long and Short of Long-Term Memory", a conceptual review published in 1986 in Nature. In this paper, we proposed that if gene expression was required to convert short-term memory at a synapse into long-term memory, then the synapse stimulated by learning somehow had to send a signal to the nucleus telling it to turn on certain regulatory genes. In short-term memory, synapses use cyclic AMP and protein kinase A inside the cell to call for the release of more neurotransmitters. Goelet and I hypothesized that in long-term memory this kinase moves from the synapse to the nucleus, where it somehow activates proteins that regulate gene expression.

cAMP PKA MAPK CREB
  • We now collaborated with Roger Tsien at the University of California, San Diego and used a method developed by him that allowed us to visualize the location of the cyclic AMP and protein kinase A in the neuron. We found that whereas a single pulse of serotonin increases cyclic AMP and protein kinase A primarily at the synapse, repeated pulses of serotonin produce even higher concentrations of cyclic AMP, causing protein kinase A to move into the nucleus, where it activates genes. Later studies found that protein kinase A recruits another kinase, called MAP kinase, which is also associated with synaptic growth and also migrates to the nucleus. Thus we confirmed our idea that one of the functions of repeated sensitization training -- why practice makes perfect -- is to cause the appropriate signals in the form of kinases to move into the nucleus.
  • Once in the nucleus, what do these kinases do? We knew from recently published studies of non-neuronal cells that protein kinase A can activate a regulatory protein called CREB (cyclic AMP response element-binding protein), which binds to a promoter (the cyclic AMP response element). This suggested to us that CREB might be a key component of the switch that converts short-term facilitation of synaptic connections to long-term facilitation and the growth of new connections.
  • An environmental stimulus -- a shock to an animal's tail activates modulatory interneurons that release serotonin. The serotonin acts on the sensory neuron to increase cyclic AMP and to cause protein kinase A and MAP kinase to move to the nucleus and activate CREB. The activation of CREB, in turn, leads to the expression of genes that changes the function and the structure of the cell.
  • In 1995 Bartsch found that there are in fact two forms of the CREB protein, much as the model of Jacob and Monod might have predicted: one that activates gene expression (CREB-1), and one that suppresses gene expression (CREB-2). Repeated stimulation causes protein kinase A and MAP kinase to move to the nucleus, where protein kinase A activates CREB-1 and MAP kinase inactivates CREB-2. Thus long-term facilitation of synaptic connections requires not only a switching on of some genes, but also the switching off of others.
Specific Synapses?
  • A single sensory neuron has 1200 synaptic terminals and makes contact with about 25 target cells: gill motor neurons, siphon motor neurons, inking motor neurons, and excitatory and inhibitory interneurons.
  • Individual synapses can be modified independently.
Local Protein Synthesis
  • In the early 1980s Oswald Steward, now at the University of California, Irvine, had discovered that even though the vast majority of protein synthesis takes place in the cell body of the neuron, some also occurs locally, at the synapses themselves.
  • The proteins synthesized in the cell body and shipped to the terminals are sufficient to initiate synaptic growth, but to sustain that growth, proteins synthesized locally are necessary.

Memory is far more complicated...

Read More

2022-09-04
Look on Down From the Bridge

Look on down from the bridge
There’s still fountains down there

Look on down from the bridge
It’s still raining, up here

Everybody seems so far away from me
Everybody just wants to be free

Look away from the sky
It’s no different when you’re leaving home

I can’t be the same thing to you now
I’m just gone, just gone

How could I say goodbye
How could I say goodbye

Goodbye

Maybe I’ll just place my hands over you
And close my eyes real tight

There’s a light in your eyes
And you know, yeah, you know

Look on down from the bridge
I’m still waiting for you

I guess it comes down to a simple choice, really, get busy living or get busy dying.
—— Shawshank Redemption

I would like to get busy dying in love.


The Tree on the Hill

ZARATHUSTRA’s eye had perceived that a certain youth avoided him. And as he walked alone one evening over the hills surrounding the town called “The Pied Cow,” behold, there he found the youth sitting leaning against a tree, and gazing with wearied look into the valley. Zarathustra then laid hold of the tree beside which the youth sat, and spoke thus:
　“If I wished to shake this tree with my hands, I should not be able to do so.
　But the wind, which we do not see, troubles and bends it as it lists. We are worst bent and troubled by invisible hands.”
　Then the youth arose disconcerted, and said: “I hear Zarathustra, and just now was I thinking of him!”

Zarathustra answered:
　“Why are you frightened on that account? - But it is the same with man as with the tree.
　The more he seeks to rise into the height and light, the more vigorously do his roots struggle earthward, downward, into the dark and deep - into evil.”
　“Yes, into evil!” cried the youth. “How is it possible that you have discovered my soul?”
　Zarathustra smiled, and said: “Many a soul one can never discover, unless one firsts invents it.”
　“Yes, into evil!” cried the youth once more.
　“You said the truth, Zarathustra. I trust myself no longer since I sought to rise into the height, and nobody trusts me any longer; how does that happen?
　I change too quickly: my today refutes my yesterday. I often overleap the steps when I climb; none of the steps pardons me for it.
　When aloft, I find myself always alone. No one speaks to me; the frost of solitude makes me tremble. What do I seek in the heights?
　My contempt and my longing increase together; the higher I climb, the more do I despise him who climbs. What does he seek in the heights?
　How ashamed I am of my climbing and stumbling! How I mock my violent panting! How I hate him who flies! How tired I am on the height!”

Here the youth was silent. And Zarathustra contemplated the tree beside which they stood, and spoke thus:
　“This tree stands lonely here on the hills; it has grown up high above man and beast.
　And if it wanted to speak, there would be no one who could understand it: so high has it grown.
　Now it waits and waits, - for what does it wait? It dwells too close to the seat of the clouds; it waits - for the lightning?”
　When Zarathustra had said this, the youth called out with violent gestures: “Yes, Zarathustra, you speak the truth. I longed for my destruction, when I wanted to be in the heights, and you are the lightning for which I waited! Behold, what have I been since you have appeared amongst us? It is my envy of you that has destroyed me!” - Thus spoke the youth, and wept bitterly. Zarathustra, however, put his arm about him, and led the youth away with him.

And when they had walked a while together, Zarathustra began to speak thus:
　It rends my heart. Better than your words can express it, your eyes tell me all your danger.
　You are not yet free; you still search for freedom. You are too weary from your search, and too wakeful.
　You aspire to the heights; you thirst for the stars. But your evil impulses also thirst for freedom.
　Your wild dogs want freedom; they bark for joy in their cellar when your spirit trys to open all prison doors.
　To me you are still a prisoner who seeks his freedom: ah! in such prisoners the soul becomes clever, but also deceitful and wicked.
　And the liberated spirit must still purify himself. Much of the prison and the mould still remains in him: his eye has still to become pure.
　Yes, I know your danger. But by my love and hope I beseech you: do not throw away your love and hope!

　You still feel noble, and others still feel your nobility, though they bear you a grudge and cast evil glances. Know that the noble one stands in everyones way.
　To the good, also, a noble one stands in the way: and even when they call him a good man, they want to push him aside.
　The noble man would create the new, and a new virtue. The good want the old, and that the old should be preserved.
　But it is not the danger of the noble man that he might become one of the good, but that he might become a blusterer, a scoffer, or a destroyer.
　Ah! I have known noble ones who lost their highest hope. And then they slandered all high hopes.
　Then they lived shamelessly in brief pleasures, only lived from day to day.
　“Spirit too is lust,” - they said. The wings of their spirit are broken; and now their spirit crawls about, and defiles what it gnaws.
　Once they thought of becoming heroes; now they are libertines. The idea of the hero offends and troubles them.
　But by my love and hope I beseech you: do not throw away the hero in your soul! Keep sacred your highest hope! -

Thus spoke Zarathustra.

ーー「Thus Spoke Zarathustra」, Chapter 8

The youth want to find his personal meanings.
To be a hero in love. Keep sacred his highest hope.

To be a Hero or a part of Christ?
Be a Gambler and take the adventure. Get busy dying in love.

山上的树

　　查拉斯图拉发现一个少年总是回避他。某晚，他往彩牛城边的高山上去散步，吓，他看见这少年靠着树坐着，疲乏的目光望着深谷。查拉斯图拉抱着这少年倚坐的那棵树说：
　　“如果我想用手去摇撼这棵树，我不能够。
　　但是，我们不能看见的风，却随意地摇撼它弯屈它。同样地，我们也被不能看见的手所弯屈所摇撼。”
　　这少年突然地立起，他说：“我听到查拉斯图拉说话了，我正想着他！”

　　查拉斯图拉答：
　　“你为什么惊怕呢？——人与树是一样的。
　　他越想向光明的高处生长，他的根便越深深地伸入土里，黑暗的深处去，——伸入恶里去。”
　　“是的，伸入恶里去！”少年喊叫起来。“你如何能够发现我的灵魂呢？”
　　查拉斯图拉微笑地说：“许多灵魂，除非先被制造了，是永不会被发现的。”
　　“是的，伸入恶里去！”这少年又喊叫起来。
　　“你说的全是真理，查拉斯图拉。自从我想升往高处去，我对自己便无信心，也无人信任我；——这是何故呢？轻蔑那想升高的人。他到底想在高处做什么呢？
　　我如何地自惭于我的升高与我的碰跌呵！我如何地讥讪我的急喘呵！我如何地恨那飞着的呵！当我在高处我是如何地疲倦呵！”

　　于是少年沉默下来。查拉斯图拉看着他俩旁边那棵树如是说：
　　“这树独自在山上高大起来；它在人与兽之上成长着。
　　如果它想说话，任何人不能了解它，它长得太高了。
　　于是它等候着，等候着——等候什么呢？它住得太靠近云座了：它或许等候雷火第一击罢？”
　　查拉斯图拉说完以后，这少年作激烈的手势叫道：“是的，查拉斯图拉，你说的全是真理。我之想达到高处，只是渴求我自己的没落，而你便是我等候的雷火之一击！你看我罢，自从你来到这里以后，我成了什么？这是对于你的妒忌杀了我！”——少年如是说，而痛哭起来。查拉斯图拉用臂挽住他的腰，把他牵走。

　　他俩并肩地走了几分钟，查拉斯图拉又如是说：
　　“我心痛极了。你的目光诉说着你所冒的危险比你的语言还清楚些。
　　你还是不自由的；你仍找寻着自由。你的找寻使你如梦游者似地清醒。
　　你想往自由的高处去，你的灵魂渴求着星球。但是你的恶劣的本能也热望着自由。
　　你的野犬也想解放自己；当你的精神尝试开狱门时，它们在地窖里欢叫着。
　　在我看来，你还是一个幻想着自由的囚犯：唉！这种囚犯之灵魂，变成机智的，同时变成狡狯的恶劣的。
　　精神自由了的人，还得净化自己。在他心里还有许多禁锢和泥垢；你的眼睛也得变成纯洁的。
　　是的，我知道你的危险。但是凭着我的爱与希望，我请求你：莫抛弃你的爱与你的希望罢！

　　你还觉得你自己高贵，便是恨你，用恶意的目光看你的人，也认为你高贵。你得知道：无论何人总把一个高贵的人当成一个阻碍物。
　　高贵的人也是善良者之阻碍物：虽然善良者也称他善良，那只是把他丢放在旁边。
　　高贵的人想创造新事物与新道德。善良的人们却需要旧事物，保存旧事物。
　　高贵的人之危险，不是他会变成善良者，而是他会变成无耻者，讥讪者，破坏者。
　　唉！我曾知道许多高贵的人，失去了他们最高的希望。于是他们毁谤一切高贵的希望。
　　于是他们无耻地生活于短促的快乐上，他们没有隔夜的计划。
　　‘精神也是一种淫乐。’——他们如是说。于是他们的精神自折断了翼：他们现在爬着，弄脏一切他们咬吃之物。
　　从前他们想成英雄；现在他们仅是享乐者。英雄这观念使他们痛苦惧怕。
　　但是凭着我的爱与希望，我请求你：莫抛弃你灵魂里的英雄罢！神圣化你最高的希望罢！”

　　查拉斯图拉如是说。

ーー《查拉斯图拉如是说》，第一卷

保罗灵魂里的英雄 =>

我已经和基督同钉了十字架；现在活着的、不再是我了，乃是基督在我里面活着。我如今在肉身上活的、乃是在于信上帝的儿子而活的；他爱了我，为我舍弃自己。
(加拉太书 2:20 吕振中)

お待ちくださいませ。

一幅痛苦、一幅可怕的景象浮现在我面前：我揭开了人之败坏的幕帘。在我的口中，败坏这个词至少排除了这样一种疑惑：它包含了某种对人的道德谴责。败坏的意思——我想再次强调一遍——是非道德化的：这种非道德化到了这种程度，以至于在迄今为止人们最有意识地追求“德性”和“神性”的地方，我却恰恰强烈地感受到了那种败坏。人们或许已经猜到，我在颓废的意义上来理解败坏：我的看法是，人类现在用来概括最高愿望的一切价值都是颓废的价值。
倘若一个动物、一个物种、一个个体丧失其本能，倘若它们选择、偏爱那些对自己有害的东西，那么我就称其为败坏。一个关于“更高情感”和“人类理想”的历史——我有可能不得不讲述这个历史——几乎就是在说明，人为什么如此败坏。在我看来，生命本身就是追求力量增长、追求力量持存、追求力量积累、追求权力的本能：只要没有权力意志，那就只有衰亡。我的看法是，人类的一切最高价值都缺乏这种意志——衰亡的价值、虚无主义的价值以最神圣的名义占据统治地位。
ーー《敌基督者》，6

如果说我对这位伟大的象征主义者有什么理解，那就是：他仅仅把“内心”的实在当成实在，当成“真理”——他把其余的东西，把一切自然、时间、空间、历史之物都仅仅理解为象征，理解为隐喻的契机。
ーー《敌基督者》，34

面对着如同死去般的痛苦和虚空；敢于冒死，行动起来；去迎接久远的安息吧，直到世界末日。
勇敢的冒险者所拥有的从死里复活之意志：真正的坚强是勇敢如爱如死之坚强。冒险者有多么强烈的冒死意志，就有多么强壮。

This is what the LORD says: “Only if the heavens above can be measured and the foundations of the earth below be searched out will I reject all the descendants of Israel because of all they have done,” declares the LORD.

(Jeremiah 31:37 NIV)

耶和华这样说：
『人若能量度在上的诸天，
测透地下面的根基，
我也就会因以色列后裔所作的一切，
弃绝他们众人。』
这是耶和华的宣告。

(耶利米书 31:37 新译本)

“The days are coming,” declares the LORD , “when this city will be rebuilt for me from the Tower of Hananel to the Corner Gate. The measuring line will stretch from there straight to the hill of Gareb and then turn to Goah. The whole valley where dead bodies and ashes are thrown, and all the terraces out to the Kidron Valley on the east as far as the corner of the Horse Gate, will be holy to the LORD . The city will never again be uprooted or demolished.”

(Jeremiah 31:38-40 NIV)

『看哪！日子快到（这是耶和华的宣告），这城从哈楠业城楼直到角门，必为耶和华重建起来。量度的准绳还要往外量，直到迦立山，绕到歌亚。抛尸和倒灰的整个山谷，以及从汲沦溪直到东边马门拐角一带所有的墓地，都必归耶和华为圣，永远不再拔出，不再倾覆。』

(耶利米书 31:38-40 新译本)

The Lord Jesus, after being conceived, tested, and crucified on the altar, shedding His precious blood, was resurrected to become the heavenly High Priest, ascended into heaven with His blood to enter the Holy of Holies, and His Spirit became the life-giving Spirit, indwelling our spirit, joining our spirit to the heavens and bringing heaven into our spirit. We shall go outside the camp and enter into the innermost part of the divine tabernacle.

主耶稣经过成孕（约 1:14）、受试（约 6:15）、在祭坛上被钉死流出宝血（约 19:34），复活成为属天的大祭司（约 20:14），带着血升天进入至圣所（约 20:17）。他的灵成为赐生命的灵，内住在我们的灵里面（约 20:22），将我们的灵联于天，也将天带到我们的灵里。我们要出到宿营的外面，进入神圣帐幕的最里面。

主しゅイエスは、母ははの胎はらに宿やどられ、試こころみに会あい、祭壇さいだんの上うえで釘くぎづけにされて尊たっとい血ちを流ながされ、復活ふっかつして天的てんてきな大だい祭司さいしとなられ、血ちを携たずさえて天てんに昇のぼり、至聖所しせいじょに入はいられました。そして、彼かれの霊れいは、命いのちを与あたえる霊れいとなられ、私わたしたちの霊れいの中なかに住すまわれ、私わたしたちの霊れいを天てんに結むすびつけ、また天てんを私わたしたちの霊れいの中なかにもたらされました。私わたしたちも、営所えいしょの外そとに出でて、神聖しんせいな幕屋まくやの最もっとも奥おくへ入はいりましょう。

耶稣的灵是由从马利亚而来的人的灵和自有永有的圣灵调和而成，并随着耶稣经历受试、钉死、下到阴间、拿到阴间的钥匙并复活升天的过程。
他的肉骨成了赐肉骨的灵。他的灵成了赐灵的肉骨。


Gamble well in love. Prepare for the worst, make bold choices and embark on adventures with the strongest determination. Go outward to the farthest, inward to the deepest, in pursuit of the ultimate facts.

好好地赌博吧。做最坏的打算、怀着最坚定的决心，勇敢地做出选择、踏上冒险旅程。向外往最远处去、向内往最深处去，追求终极真实。

良く賭けましょう。最悪の事態に備え、強い決意を持ち、大胆な選択をして、冒険に出かけましょう。外側に最も遠いところに、内側に最も深いところに、究極の真実を追い求めてください。

上帝说：『我们要造人，按着我们的形像，照我们的样式来造；让他们管理海里的鱼、空中的飞鸟，也管理牲口、以及全地、和爬在地上的各样爬行动物。』上帝就按自己的形像创造人：按上帝的形像创造他：创造他们有男有女。上帝就给他们祝福说：『要繁殖增多，充满全地，去征服它；也要管理海里的鱼、空中的飞鸟、和在地上行动的各样活物。』
(创世记 1:26-28 吕振中)

第六日，让我们恢复创造力。创造更有爱的自己。追求终极真实。

We can be both of God and the devil. Since we’re trying to raise the dead against the stream of time.
ーー Vermouth, Detective Conan

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2022-08-20
枯れない花

The Blood of Lambs: A Former Terrorist’s Memoir of Death and Redemption, Kamal Saleem.


from IPython.display import YouTubeVideo
YouTubeVideo(‘oJk-u_TTiQo’, style=’width: 90%; aspect-ratio: 16/9;’)

枯れない花

心に 小さな花が 咲いてる
こころに ちいさなはなが さいてる
心中盛开着一朵小小的花。

君から もらった 枯れない花が
きみから もらった かれないはなが
是你给我的永不凋谢的花朵。

信じることを もう 怖がらないくらい
しんじることを もう こわがらないくらい
已经不怎么害怕自己所相信的，

强くなれたから
つよくなれたから
因为我变得坚强了。

君に逢えて うれしかった
きみにあえて うれしかった
能遇见你，我很高兴。

つないだ手が 夸りだった
つないだてが ほこりだった
能牵着手，是我的荣幸。

今は 别々の空 见上げていても
いまは べつべつのそら みあげていても
尽管我们现在正仰望着不同的天空。

ほら 歩ける ひとりでも
ほら あるける ひとりでも
我一个人也能继续走下去。

悲しい時ほど 笑う私を
かなしいときほど わらうわたしを
在悲伤的时候却仍然绽放笑容的我

何にも 言わないで 抱いてくれたね
なんにも いわないで だいてくれたね
一言不发地被你抱住了。

冻りついたドアが そっと开くような
こおりついたドアが そっとひらくような
仿佛冰冻的门扉渐渐地融化。

そんな気がしたよ
そんなきがしたよ
我有这样的感觉。

君に逢えてうれしかった
きみにあえてうれしかった
能与你相遇我真的很高兴。

孤独さえも 分かち合えた
こどくさえも わかちあえた
连孤独都能一起分享。

今も この空の下 つながっていると
いまも このそらのした つながっていると
现在，我们仍在这片天空下紧紧相连。

そう思える 离れても
そうおもえる はなれても
是的，我仍这样认为，即便是分离两地。

「ありがとう。」も 言えなかった
「ありがとう。」も いえなかった
还没能说出感谢的话语。

约束さえ できなかった
やくそくさえ できなかった
甚至连约定也没有做出。

だけど あの日と 同じ风がふいたら
だけど あのひと おなじかぜがふいたら
但我仍相信，当被和那天一样的风吹拂的时候，

また 必ず 逢えるよね
また かならず あえるよね
我们一定可以再度相见。

君に 逢えて うれしかった
きみに あえて うれしかった
能与你相遇我真的很高兴。

つないだ手が 夸りだった
つないだてが ほこりだった
能与你牵手是我的骄傲。

今は 别々の空 见上げていても
いまは べつべつのそら みあげていても
尽管我们现在正仰望着不同的天空。

ほら 歩ける ひとりでも
ほら あるける ひとりでも
我一个人也能继续走下去。

A small flower is blooming inside my heart,
The undying flower you gave to me,
I was able to believe strongly enough in myself,
So I’m not afraid anymore…

※ I was happy meeting you,
And proud of our holding hands,
Even though we look up to different skies now,
See? I can walk on my own now…

I laugh more during sad times,
To hide the pain I feel inside,
But you hugged me gently without saying a thing
I felt as if it were like opening a door frozen in ice…

I was happy meeting you,
Even though I could only share my loneliness,
Even though we’re separated now,
I still feel that we’re somehow connected under this sky…

I didn’t say thank you…
I couldn’t even promise…
However, like on that day, if the wind blows
Then I know we will surely meet again…

(Repeat ※)
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